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Caulophyllogenin

Caulophyllogenin
Caulophyllogenin is a partial PPARγ agonist (EC50 = 12.6 μM) derived from the stem bark of Kalopanax pictus (Araliaceae). Caulophyllogenin inhibits pro-inflammatory cytokine secretion and can be used in studies about the prevention and treatment of inflammatory diseases, type-2 diabetes, obesity and metabolic syndrome.
Catalog No. TN1475Cas No. 52936-64-8
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Purity:98.56%
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Caulophyllogenin

Purity: 98.56%
Catalog No. TN1475Alias Segetalic acidCas No. 52936-64-8

Caulophyllogenin is a partial PPARγ agonist (EC50 = 12.6 μM) derived from the stem bark of Kalopanax pictus (Araliaceae). Caulophyllogenin inhibits pro-inflammatory cytokine secretion and can be used in studies about the prevention and treatment of inflammatory diseases, type-2 diabetes, obesity and metabolic syndrome.
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Pack SizePriceAvailabilityQuantity
1 mg$113In Stock
5 mg$267In Stock
10 mg$392In Stock
25 mg$656In Stock
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Product Introduction

Bioactivity
Description
Caulophyllogenin is a partial PPARγ agonist (EC50 = 12.6 μM) derived from the stem bark of Kalopanax pictus (Araliaceae). Caulophyllogenin inhibits pro-inflammatory cytokine secretion and can be used in studies about the prevention and treatment of inflammatory diseases, type-2 diabetes, obesity and metabolic syndrome.
Targets&IC50
PPARγ:12.6 μM (EC50)
In vitro
Caulophyllogenin inhibits IL-12 p40, IL-6, and TNF-α with IC50s ranging from 3.3 to 20.0 μM[1].
AliasSegetalic acid
Chemical Properties
Molecular Weight488.7
FormulaC30H48O5
Cas No.52936-64-8
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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