Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ch55 (3,5-Di-tert-butylchalcone) is an effective inducer of the differentiation of HL60 cells (EC50 = 200 nM) and shows high affinity with RAR-α and RAR-β receptors. Ch55 can be used in studies about cancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 41.00 | |
5 mg | In stock | $ 97.00 | |
10 mg | In stock | $ 147.00 | |
25 mg | In stock | $ 286.00 | |
50 mg | In stock | $ 522.00 | |
100 mg | In stock | $ 759.00 | |
500 mg | In stock | $ 1,580.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 106.00 |
Description | Ch55 (3,5-Di-tert-butylchalcone) is an effective inducer of the differentiation of HL60 cells (EC50 = 200 nM) and shows high affinity with RAR-α and RAR-β receptors. Ch55 can be used in studies about cancer. |
In vitro | In rabbit tracheal epithelial cells, Ch55 inhibits type I transglutaminase activity (EC50 = 0.02 nM) and increases cholesterol sulfate levels (EC50 = 0.03 nM) thereby inhibiting squamous cell differentiation. Ch55 inhibits the induction of ornithine decarboxylase activity in 3T6 fibroblasts (EC50 = 1 nM) and induces cell differentiation of embryonic carcinoma F9 cells and melanoma S91 cells (EC50 = 0.26 and 0.5 nM). Ch55 shows a low affinity for cellular retinoic acid binding protein[1]. |
Synonyms | Ch-55, CH 55, 3,5-Di-tert-butylchalcone |
Molecular Weight | 364.48 |
Formula | C24H28O3 |
CAS No. | 110368-33-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 40 mg/mL (109.7 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Ch55 110368-33-7 Metabolism Retinoid Receptor Ch-55 CH 55 3,5-Di-tert-butylchalcone inhibitor inhibit