Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
20 mg | In stock | $ 60.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects. |
In vitro | In C57BL/6J mice fed a high-fat diet, oral administration of 20-Hydroxyecdysone (10 mg/kg/day, for 13 weeks) was able to improve obesity and insulin levels, reducing body weight and body fat content. |
In vivo | In cells induced by CoCl2, 20-Hydroxyecdysone reduces the production of reactive oxygen species (ROS), diminishes mitochondrial membrane depolarization, and suppresses the release of cytochrome c into the cytoplasm, thereby ameliorating cell damage. In H4IIE cells, 20-Hydroxyecdysone effectively lowers the expression of phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-phosphatase (G6Pase), resulting in decreased glucose production. |
Source |
Synonyms | Commisterone, B-ecdysone,Commisterone, 20-Hydroxyecdysone, Ecdysterone, B-ecdysone, Hydroxyecdysone |
Molecular Weight | 480.63 |
Formula | C27H44O7 |
CAS No. | 5289-74-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 89 mg/mL (185.2 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: 89 mg/mL (185.2 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Crustecdysone 5289-74-7 Apoptosis Autophagy Metabolism Others Proteases/Proteasome Caspase Endogenous Metabolite hormone Commisterone metabolite B-ecdysone,Commisterone ecdysis Ecdysone arthropods metamorphosis inhibit 20-Hydroxyecdysone Inhibitor α-Ecdysone Ecdysterone ecdysteroid active B-ecdysone Hydroxyecdysone inhibitor