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Taurodeoxycholic acid sodium hydrate

🥰Excellent
Catalog No. TJA2398Cas No. 110026-03-4
Alias Taurohyodeoxycholic acid sodium salt, Taurodeoxychloic Acid sodium hydrate, Sodium taurodeoxycholate monohydrate

Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, influences bile salt and biliary lipid secretion in rats.

Taurodeoxycholic acid sodium hydrate

Taurodeoxycholic acid sodium hydrate

🥰Excellent
Purity: 98.87%
Catalog No. TJA2398Alias Taurohyodeoxycholic acid sodium salt, Taurodeoxychloic Acid sodium hydrate, Sodium taurodeoxycholate monohydrateCas No. 110026-03-4
Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, influences bile salt and biliary lipid secretion in rats.
Pack SizePriceAvailabilityQuantity
10 mg$30In Stock
25 mg$60In Stock
50 mg$89In Stock
100 mg$129In Stock
1 mL x 10 mM (in DMSO)$29In Stock
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Purity:98.87%
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Product Introduction

Bioactivity
Description
Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, influences bile salt and biliary lipid secretion in rats.
In vivo
At all infusion rates, taurohyodeoxycholic acid caused a greater (P < 0.001) secretion of biliary lecithin compared to the other bile salts. There were no significant differences in the biliary secretion of cholesterol and proteins. Electron microscopy showed the recruitment of vesicles and lamellar bodies around and within bile canaliculi. In conclusion, taurohyodeoxycholic promotes a biliary lecithin secretion greater than expected from physicochemical predictions, representing a novel secretory property with potential pharmacological relevance[1].
AliasTaurohyodeoxycholic acid sodium salt, Taurodeoxychloic Acid sodium hydrate, Sodium taurodeoxycholate monohydrate
Chemical Properties
Molecular Weight539.70
FormulaC26H46NNaO7S
Cas No.110026-03-4
SmilesC[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(NCCS(=O)([O-])=O)=O)([H])[C@@]3([H])[C@@](C[C@@H]1O)([H])[C@@]4([C@](C[C@@H](CC4)O)([H])CC3)C.[Na+].O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 125 mg/mL (231.18 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8529 mL9.2644 mL18.5288 mL92.6441 mL
5 mM0.3706 mL1.8529 mL3.7058 mL18.5288 mL
10 mM0.1853 mL0.9264 mL1.8529 mL9.2644 mL
20 mM0.0926 mL0.4632 mL0.9264 mL4.6322 mL
50 mM0.0371 mL0.1853 mL0.3706 mL1.8529 mL
100 mM0.0185 mL0.0926 mL0.1853 mL0.9264 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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