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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $155 | In Stock | |
5 mg | $473 | In Stock | |
10 mg | $679 | In Stock | |
25 mg | $987 | In Stock | |
50 mg | $1,380 | In Stock |
Description | Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling pathways. Arnicolide D inhibits Nasopharyngeal carcinoma (NPC) cell viability in a concentration- and time-dependent manner. Arnicolide D exerts strong cytotoxic activity on the human colon carcinoma HT-29 cell line. |
In vitro | In this study, we found that two sesquiterpene lactones, isobutyroylplenolin and Arnicolide D, from Centipeda minima L. (Compositae) exerted stronger cytotoxic activity than cisplatin on the human colon carcinoma HT-29 cell line. Furthermore, the cytotoxicity of these two compounds on normal cells was weaker than that of cisplatin. |
Molecular Weight | 332.39 |
Formula | C19H24O5 |
Cas No. | 34532-68-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||
Solubility Information | DMSO: 2.75 mg/mL (8.27 mM) | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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