Powder: -20°C for 3 years | In solvent: -80°C for 1 year
D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 55.00 | |
10 mg | In stock | $ 97.00 | |
25 mg | In stock | $ 196.00 | |
50 mg | In stock | $ 365.00 | |
100 mg | In stock | $ 557.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 61.00 |
Description | D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation. |
Targets&IC50 | TSHR:11.6 μM(EC50) |
In vitro | D3-βArr stimulated β-Arr 1 translocation with an efficacy threefold greater than TSH. The EC50 for β-Arr 1 translocation by D3-βArr was 11.6 μM. D3-βArr (10 μM) increased the efficacy of TSH in the translocation of β-Arr 1 at a maximum of 5.1-fold over TSH alone. |
Synonyms | NCGC00379308 |
Molecular Weight | 333.43 |
Formula | C20H23N5 |
CAS No. | 662164-09-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (299.91 mM)
You can also refer to dose conversion for different animals. More
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D3-βArr 662164-09-2 GPCR/G Protein TSH Receptor Thyroid-stimulating hormone Receptor D3-bArr Thyrotropin receptor inhibit D3-betaArr D3βArr Inhibitor D-3-βArr NCGC 00379308 NCGC00379308 NCGC-00379308 D3 βArr inhibitor