Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Droloxifene (3-Hydroxytamoxifen), a tamoxifen derivative, is an oral active and selective estrogen receptor modulator.Droloxifene induced p53 expression and apoptosis in McF-7 cells.Fluroxifene has anti-estrogen and anti-implantation effects.Fluroxifene prevented bone loss in ovariectomized rats.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 84.00 | |
5 mg | In stock | $ 197.00 | |
10 mg | In stock | $ 297.00 | |
25 mg | In stock | $ 516.00 | |
50 mg | In stock | $ 736.00 | |
100 mg | In stock | $ 987.00 | |
500 mg | In stock | $ 1,980.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 226.00 |
Description | Droloxifene (3-Hydroxytamoxifen), a tamoxifen derivative, is an oral active and selective estrogen receptor modulator.Droloxifene induced p53 expression and apoptosis in McF-7 cells.Fluroxifene has anti-estrogen and anti-implantation effects.Fluroxifene prevented bone loss in ovariectomized rats. |
In vitro | Droloxifene induces apoptosis in MCF-7 cells(10 nM; 16-18 hours)[1]. |
In vivo | Droloxifene (5-20 mg/kg,P.o.;Daily for 4 weeks can bring THE BMD of DFM up to 10mg/kg and completely prevent OVX from reducing the BMC and BMD of DFM at 20mg /kg/day[1]. |
Synonyms | 3-Hydroxytamoxifen |
Molecular Weight | 387.51 |
Formula | C26H29NO2 |
CAS No. | 82413-20-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45.0 mg/mL (116.1 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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Droloxifene 82413-20-5 Endocrinology/Hormones Estrogen Receptor/ERR 3-Hydroxytamoxifen inhibitor inhibit