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Dropropizine

Dropropizine (UCB-1967), a racemic non-opiate antitussive agent, is served as a cough suppressant.

Catalog No. T0452Cas No. 17692-31-8

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Purity:99.93%

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COA LCMS HNMR HPLC

Dropropizine

Catalog No. T0452Cas No. 17692-31-8

Dropropizine (UCB-1967), a racemic non-opiate antitussive agent, is served as a cough suppressant.

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Pack Size	Price	Availability	Quantity
500 mg	$42	In Stock
1 mL x 10 mM (in DMSO)	$46	In Stock

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Product Introduction

Bioactivity

Description	Dropropizine (UCB-1967), a racemic non-opiate antitussive agent, is served as a cough suppressant.
Alias	(±)-Dropropizine, UCB-196, UCB-1967

Chemical Properties

Molecular Weight	236.31
Formula	C₁₃H₂₀N₂O₂
Cas No.	17692-31-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

H2O: 9 mg/mL (38.1 mM)

DMSO: 55 mg/mL (232.75 mM)

Ethanol: 44 mg/mL (186.2 mM)

Solution Preparation Table

H2O/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	4.2317 mL	21.1586 mL	42.3173 mL	211.5865 mL
5 mM	0.8463 mL	4.2317 mL	8.4635 mL	42.3173 mL
10 mM	0.4232 mL	2.1159 mL	4.2317 mL	21.1586 mL
20 mM	0.2116 mL	1.0579 mL	2.1159 mL	10.5793 mL

Ethanol/DMSO

	1mg	5mg	10mg	50mg
50 mM	0.0846 mL	0.4232 mL	0.8463 mL	4.2317 mL
100 mM	0.0423 mL	0.2116 mL	0.4232 mL	2.1159 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

peripheralantitussiveDropropizineInhibitorUCB196UCB1967UCB 196inhibitUCB 1967