antitussive

Guaiapate has an antitussive and sedative effect.

Schisantherin A (Wuweizi ester-A) is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera, has been used as an antitussive, tonic, and sedative agent.

2,3,5,6-Tetramethoxyaporphine, a benzyl isoquinoline alkaloid with antitussive properties, can be extracted from Glaucium flavum Cr. (Family Papaveraceae) [1] [2].

Homatropine hydrochloride is an orally active anticholinergic agent that induces rapid pupil dilation with cycloplegic effects and possesses antitussive properties. It is utilized in research pertaining to ocular diseases and coughs [1].

Neostenine shows significant antitussive activity.

Moguisteine (BBR-2173) is a new-type peripheral non-narcotic antitussive drug.

1. Protostemonine has anti-inflammatory activity, it effectively attenuates LPS-induced inflammatory responses in vitro and in vivo; the beneficial effects are associated with the decreased phosphorylation of MAPK and AKT and the reduced expression of pro

Dropropizine (UCB-1967), a racemic non-opiate antitussive agent, is served as a cough suppressant.

Obtucarbamate B has antitussive activity.

Obtucarbamate A isolated from Disporum cantoniense has antitussive activity.It has antitussive activity, it exhibits significant inhibitory effect against neuroinflammation with the IC50 value of 10.57 μM .

Oroxin A (Baicalein 7-O-glucoside) has antitussive and expectorant effects.

Eprazinone dihydrochloride (NSC 317935) is a mucolytic with antitussive and mucolytic effect.

Dimemorfan phosphate (3,17-dimethylmorphinan) is a sigma 1 receptor agonist. Dimemorfan phosphate is used as a potent antitussive.

Carbetapentane citrate (Pentoxyverine citrate) , an antitussive (cough suppressant), is frequently used for a cough related to illnesses like the common cold.

Carbetapentane is an antitussive anticonvulsant non-opiod agonist that acts on sigma sites.

Ligularine is a hepatotoxic otonecine-type pyrrolizidine alkaloid isolated from Ligularia hodgsonii, a Chinese traditional antitussive medicine.

Glycyrrhetinic acid-d3 is a deuterated compound of Glycyrrhetinic acid. Glycyrrhetinic acid has a CAS number of 1449-05-4. Enoxolone (INN, BAN; also known as glycyrrhetinic acid) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb licorice. It is used in flavoring and it masks the bitter taste of drugs like aloe and quinine. It is effective in the treatment of peptic ulcer and also has expectorant (antitussive) properties.

Butopiprine is a cough suppressant with antispasmodic, local anesthetic and antitussive activity.

Erioside (mulberroside B) can antitussive, antiasthmatic, hypoglycemic, anti-tumor, treatment of gout.

Diphenhydramine hydrochloride (DPH) is a histamine H1 antagonist used as an antitussive and antiemetic. It is also used for pruritus and dermatoses, for hypersensitivity reactions, as an antiparkinson, a hypnotic, and as an ingredient in common cold preparations.

Glaucine has antitussive, antioxidative potential and antiviral activities, it may be an anti-arthritic agent, it can enhance LPS and zymosan-induced IL-10 production. Glaucine can inhibit the migration and invasion of human breast cancer cells by MMP-9 i

Methyl demethoxycarbonylchanofruticosinate exhibits significant antitussive activity in a citric acid induced guinea pig cough model.

Epigambogic acid is a small molecule compound from Garcinia Cambogia with anti-tumor, antitussive, expectorant and anti-inflammatory activities.

Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruitment and M2 polarization of macroph

Isoverticine exhibits significant antitussive, expectorant and anti-inflammatory activities, it also displays significant cytotoxicity.

Dioxethedrin HCl is the ephedrine derivative. It is the beta-adrenergic agonist. As a bronchodilator and sympathomimetic agent is was used in antitussive syrup Bexol.

Benzonatate is an antagonist of sodium channel protein.

Carcainium chloride (Carcainium (chloride)) is a derivative of Lidocaine and possesses an antitussive effect.

Clobutinol hydrochloride, an antitussive agent, influences heart rate and blood pressure, and is utilized in cough-related research [1] [2] [3].

Levodropropizine ((S)-(-)-Dropropizine) is a histamine receptor inhibitor. It is used as an effective and very well tolerated peripheral antitussive drug.

Nepinalone is an alchilaminate derivative of β-tetralone. Nepinalone is an orally active cough suppressant that possesses a non-opioid antitussive activity [1].

Diphenhydramine (Syntedril), a first-generation antihistamine possessing antiemetic, antitussive, anticholinergic, and sedative properties, is mainly used in the treatment of allergies. Diphenhydramine is also used in the management of drug-induced parkinsonism and other extrapyramidal symptoms.

Sulfogaiacol (guaiacolsulfonate) is an antitussive agent, used for acute respiratory tract infections and cough.

Nepinalone hydrochloride, a non-opioid antitussive, is an alchilaminate derivative of β-tetralone. This orally active compound effectively suppresses coughing.

L-Cysteine methyl ester hydrochloride (L-Cysteine methyl ester hydrochloride (Acdrile)) is an antitussive and an expectorant agent, used to relieve breathing difficulties caused by mucus.

1. Isoliquiritin (Neoisoliquritin) has antitussive effects. 2. Isoliquiritin has antidepressant-like effects. 3. Isoliquiritin, liquiritin and isoliquirigenin inhibits the p53-dependent pathway and shows crosstalk between Akt activities.

Parapenzolate bromide is an orally active mAChR antagonist. parapenzolate bromide is an anticholinergic and antitussive agent.

Vasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease.(S)-Vasicinone exhibits antiproliferative activity against human gastric cancer cells MCG-803.

Pimethixene maleate (Pimetixene maleate) is a potent 5-HT2B receptor antagonist with sedative and antitussive activity.Pimethixene maleate inhibits 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2, and can be used in studies of dry and irritant cough in children. irritant cough in children.

DF-1012 is a 5-HT3 receptor antagonist and is also an orally-available antitussive, antiasthmatic and anti-inflammatory drug.

Tipepidine is a non-narcotic antitussive with an antidepressant-like effect. Tipepidine reversibly inhibits dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK) ) (IC 50 = 7.0 μM) and subsequently activates VTA dopamine neurons.

18α-Glycyrrhetinic acid (Enoxolone) is an inhibitor of NF-kB and an activator of the proteasome, and functions as a longevity-promoting and anti-aggregation factor in multicellular organisms. It induces apoptosis.