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Benzonatate

🥰Excellent
Catalog No. T19644Cas No. 104-31-4

Benzonatate is an antagonist of sodium channel protein.

Benzonatate

Benzonatate

🥰Excellent
Purity: 99.75%
Catalog No. T19644Cas No. 104-31-4
Benzonatate is an antagonist of sodium channel protein.
Pack SizePriceAvailabilityQuantity
5 mg38 €In Stock
10 mg62 €In Stock
25 mg125 €In Stock
50 mg187 €In Stock
100 mg315 €In Stock
1 mL x 10 mM (in DMSO)51 €In Stock
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Purity:99.75%
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Product Introduction

Bioactivity
Description
Benzonatate is an antagonist of sodium channel protein.
In vivo
Na(+) currents are inhibited most potently by a benzonatate fraction containing the 9-ethoxy component.?Detectable effects of benzonatate occur at concentrations as low as 0.3 μM, which has been reported in humans. benzonatate has local anesthetic-like effects on voltage-gated sodium channels, including Nav1.7, which is a possible mechanism for cough suppression by the drug.
Chemical Properties
Molecular Weight603.74
FormulaC30H53NO11
Cas No.104-31-4
SmilesCCCCNc1ccc(cc1)C(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOC
Relative Density.1.096 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (91.1 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6563 mL8.2817 mL16.5634 mL82.8171 mL
5 mM0.3313 mL1.6563 mL3.3127 mL16.5634 mL
10 mM0.1656 mL0.8282 mL1.6563 mL8.2817 mL
20 mM0.0828 mL0.4141 mL0.8282 mL4.1409 mL
50 mM0.0331 mL0.1656 mL0.3313 mL1.6563 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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