Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Emtricitabine, a potent nucleoside reverse transcriptase inhibitor, is employed for managing HIV infection. Emtricitabine S-oxide, also known as Emtricitabine sulfoxide, represents a significant degradation byproduct of Emtricitabine.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 4-5 weeks | $ 123.00 | |
10 mg | 4-5 weeks | $ 950.00 |
Description | Emtricitabine, a potent nucleoside reverse transcriptase inhibitor, is employed for managing HIV infection. Emtricitabine S-oxide, also known as Emtricitabine sulfoxide, represents a significant degradation byproduct of Emtricitabine. |
In vitro | Emtricitabine, an antiretroviral agent, undergoes degradation under various stress conditions—acidic, basic, and oxidative—resulting in over 51%, 13%, and 53% degradation respectively, and yielding three major degradation products (Degradant-I to Degradant-III). This process aligns with ICH guidelines to elucidate degradation pathways and identify degradation products of emtricitabine. |
Synonyms | Emtricitabine Degradant-III, Emtricitabine sulfoxide |
Molecular Weight | 263.25 |
Formula | C8H10FN3O4S |
CAS No. | 152128-77-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Emtricitabine S-oxide 152128-77-3 Microbiology/Virology Proteases/Proteasome Reverse Transcriptase HIV Protease Emtricitabine Degradant-III Emtricitabine Soxide Emtricitabine S oxide Emtricitabine sulfoxide inhibitor inhibit