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FDI-6

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Purity:100%

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COA HNMR LCMS

FDI-6

Catalog No. T4005Cas No. 313380-27-7

FDI-6 is an effective and selective inhibitor of FOXM1 that blocks DNA binding. FDI-6(FDI6) binds to the FOXM1 protein and specifically downregulates FOXM1-activated genes.

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Pack Size	Price	Availability
1 mg	$33	In Stock
2 mg	$47	In Stock
5 mg	$76	In Stock
10 mg	$143	In Stock
25 mg	$238	In Stock
50 mg	$321	In Stock
100 mg	$477	In Stock
1 mL x 10 mM (in DMSO)	$84	In Stock

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Product Introduction

Bioactivity

Description	FDI-6 is an effective and selective inhibitor of FOXM1 that blocks DNA binding. FDI-6(FDI6) binds to the FOXM1 protein and specifically downregulates FOXM1-activated genes.
In vitro	FDI-6 specifically downregulates FOXM1-activated genes with FOXM1 occupancy confirmed by ChIP-PCR. This small molecule-mediated effect is selective for FOXM1-controlled genes with no effect on genes regulated by homologous forkhead family factors.
Alias	FDI6, FDI 6

Chemical Properties

Molecular Weight	437.43
Formula	C19H11F4N3OS2
Cas No.	313380-27-7

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (114.3 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2861 mL	11.4304 mL	22.8608 mL	114.3040 mL
5 mM	0.4572 mL	2.2861 mL	4.5722 mL	22.8608 mL
10 mM	0.2286 mL	1.1430 mL	2.2861 mL	11.4304 mL
20 mM	0.1143 mL	0.5715 mL	1.1430 mL	5.7152 mL
50 mM	0.0457 mL	0.2286 mL	0.4572 mL	2.2861 mL
100 mM	0.0229 mL	0.1143 mL	0.2286 mL	1.1430 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

inhibitFDI-6Inhibitor