store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
G907 is a selective and potent antagonist of the small molecule ATP-binding cassette (ABC) transporter protein MsbA, with bactericidal activity, which traps MsbA in the inner lipopolysaccharide. G907 inhibits E. coli MsbA with an IC50 value of 18 nM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 166.00 |
Description | G907 is a selective and potent antagonist of the small molecule ATP-binding cassette (ABC) transporter protein MsbA, with bactericidal activity, which traps MsbA in the inner lipopolysaccharide. G907 inhibits E. coli MsbA with an IC50 value of 18 nM. |
Targets&IC50 | MsbA:18 nM |
In vitro | G907 inhibits the activity of purified Escherichia coli MsbA with an IC50 value of 18 nM over a concentration range of 0.1 nM to 100 μM[1]. G907 exhibits allosteric inhibitory activity against MsbA[2]. At 100 nM, G907 completely inhibits the transport activity of biotin-PE in liposomes containing MsbA-WT protein[1]. |
Molecular Weight | 433.93 |
Formula | C26H24ClNO3 |
CAS No. | 2244035-16-1 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (138.27 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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G907 2244035-16-1 Microbiology/Virology Antibiotic G 907 G-907 inhibitor inhibit