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Gypsogenin
Gypsogenin (639-14-5) is a naturally occurring biochemical that shows anti-ABL1 kinase and anti-chronic Myelogenous Leukemia activities.
Catalog No. T25476Cas No. 639-14-5
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Purity:99.73%
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Gypsogenin
Catalog No. T25476Cas No. 639-14-5
Gypsogenin (639-14-5) is a naturally occurring biochemical that shows anti-ABL1 kinase and anti-chronic Myelogenous Leukemia activities.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $136 | In Stock | |
| 5 mg | $332 | In Stock | |
| 10 mg | $493 | In Stock | |
| 25 mg | $788 | In Stock | |
| 50 mg | $1,120 | In Stock | |
| 100 mg | $1,490 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $368 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Gypsogenin (639-14-5) is a naturally occurring biochemical that shows anti-ABL1 kinase and anti-chronic Myelogenous Leukemia activities. |
| In vitro | Gypsogenin (1) was obtained by acidic hydrolysis from its saponin.?While the parent compound 1 acted as a selective inhibitor for butyrylcholinesterase (from equus) possessing a moderate mixed-type inhibition of the enzyme, Ki values as low as 2.67 0.59 μM were determined for (3β,4α) 3-O-acetyl-olean-12-ene-23,28-dinitrile (11) and acetylcholinesterase (AChE, from electric eel).?Thus, 11 possesses one-fifth of the inhibitory activity of the 'gold standard' galantamine hydrobromide;?this compound is one of the first pentacyclic triterpenoids described as a potent AChE-selective inhibitor |
| Molecular Weight | 470.68 |
| Formula | C30H46O4 |
| Cas No. | 639-14-5 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 27.5 mg/ml (58.42 mM)  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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