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HS220

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Purity:99.98%

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COA HPLC HNMR

HS220

Catalog No. T60011Cas No. 1570374-32-1

HS220 is an inhibitor of TAK1 which plays a key role in the signaling pathways of inflammation and cell survival.

With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.

Pack Size	Price	Availability
1 mg	$75	In Stock
5 mg	$187	In Stock
10 mg	$297	In Stock
25 mg	$491	In Stock
50 mg	$654	In Stock
100 mg	$894	In Stock
500 mg	Inquiry	In Stock
1 mL x 10 mM (in DMSO)	$197	In Stock

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Product Introduction

Bioactivity

Description

HS220 is an inhibitor of TAK1 which plays a key role in the signaling pathways of inflammation and cell survival.

Chemical Properties

Molecular Weight	323.35
Formula	C18H17N3O3
Cas No.	1570374-32-1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 45 mg/mL (139.17 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0926 mL	15.4631 mL	30.9262 mL	154.6312 mL
5 mM	0.6185 mL	3.0926 mL	6.1852 mL	30.9262 mL
10 mM	0.3093 mL	1.5463 mL	3.0926 mL	15.4631 mL
20 mM	0.1546 mL	0.7732 mL	1.5463 mL	7.7316 mL
50 mM	0.0619 mL	0.3093 mL	0.6185 mL	3.0926 mL
100 mM	0.0309 mL	0.1546 mL	0.3093 mL	1.5463 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc