Powder: -20°C for 3 years | In solvent: -80°C for 1 year
IFN alpha-IFNAR-IN-1 hydrochloride is an inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 hydrochloride inhibits MVA-induced IFN-α responses by BM-pDCs with IC50 of 2-8 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 41.00 | |
2 mg | In stock | $ 59.00 | |
5 mg | In stock | $ 96.00 | |
10 mg | In stock | $ 129.00 | |
25 mg | In stock | $ 223.00 | |
50 mg | In stock | $ 349.00 | |
100 mg | In stock | $ 522.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 98.00 |
Description | IFN alpha-IFNAR-IN-1 hydrochloride is an inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 hydrochloride inhibits MVA-induced IFN-α responses by BM-pDCs with IC50 of 2-8 μM. |
Targets&IC50 | IFNAR:2-8 μM |
In vitro | IFN alpha-IFNAR-IN-1 hydrochloride inhibited the IFN-α responses that were elicited after treatment with CpG2216, stimulation with poly(I:C), and infection with VSV-M2, whereas the total IL-12 production was notably less affected under those conditions. IFN alpha-IFNAR-IN-1 hydrochloride specifically inhibits MVA-induced IFN-α responses by BM-pDCs. IFN alpha-IFNAR-IN-1 hydrochloride exerts immunosuppressive activity by the direct interaction with IFN-α[1]. |
Molecular Weight | 315.86 |
Formula | C18H18ClNS |
CAS No. | 2070014-98-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 16 mg/mL (50.66 mM), Sonification is recommended.
DMSO: 95 mg/mL (300.77 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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IFN alpha-IFNAR-IN-1 hydrochloride 2070014-98-9 Immunology/Inflammation Others IFNAR IFN alpha-IFNAR-IN-1 Hydrochloride IFN α-IFNAR-IN-1 Hydrochloride Inhibitor Interferon-α/β receptor Interferon-alpha/beta receptor IFN a-IFNAR-IN-1 Hydrochloride inhibit IFN alpha IFNAR IN 1 hydrochloride IFN alphaIFNARIN1 hydrochloride inhibitor