Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

IHR-1

IHR-1
IHR-1 is a Potent Smo antagonist (IC50 = 7.6 nM). Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro.
Catalog No. T24159Cas No. 548779-60-8
Select Batch
Purity:97.02%
Contact us for more batch information

Resource Download

IHR-1

Purity: 97.02%
Catalog No. T24159Alias IHR 1Cas No. 548779-60-8

IHR-1 is a Potent Smo antagonist (IC50 = 7.6 nM). Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
2 mg$29In Stock
5 mg$48In Stock
10 mg$77In Stock
25 mg$140In Stock
50 mg$215In Stock
100 mg$323In Stock
200 mg$463In Stock
1 mL x 10 mM (in DMSO)$53In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "IHR-1"

Product Introduction

Bioactivity
Description
IHR-1 is a Potent Smo antagonist (IC50 = 7.6 nM). Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro.
Targets&IC50
Smo:7.6 nM
AliasIHR 1
Chemical Properties
Molecular Weight454.13
FormulaC20H12Cl4N2O2
Cas No.548779-60-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 25 mg/mL (55.05 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2020 mL11.0101 mL22.0201 mL110.1006 mL
5 mM0.4404 mL2.2020 mL4.4040 mL22.0201 mL
10 mM0.2202 mL1.1010 mL2.2020 mL11.0101 mL
20 mM0.1101 mL0.5505 mL1.1010 mL5.5050 mL
50 mM0.0440 mL0.2202 mL0.4404 mL2.2020 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy IHR-1 | purchase IHR-1 | IHR-1 cost | order IHR-1 | IHR-1 chemical structure | IHR-1 formula | IHR-1 molecular weight