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IHR-1 is a Potent Smo antagonist (IC50 = 7.6 nM). Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $29 | In Stock | |
5 mg | $48 | In Stock | |
10 mg | $77 | In Stock | |
25 mg | $140 | In Stock | |
50 mg | $215 | In Stock | |
100 mg | $323 | In Stock | |
200 mg | $463 | In Stock | |
1 mL x 10 mM (in DMSO) | $53 | In Stock |
Description | IHR-1 is a Potent Smo antagonist (IC50 = 7.6 nM). Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro. |
Targets&IC50 | Smo:7.6 nM |
Alias | IHR 1 |
Molecular Weight | 454.13 |
Formula | C20H12Cl4N2O2 |
Cas No. | 548779-60-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 25 mg/mL (55.05 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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