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IRAK4-IN-4

IRAK4-IN-4
IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.
Catalog No. T11673Cas No. 1850276-58-2
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Purity:99.52%
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IRAK4-IN-4

Catalog No. T11673Cas No. 1850276-58-2
IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.
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Pack SizePriceAvailabilityQuantity
1 mg$58In Stock
5 mg$148In Stock
10 mg$223In Stock
25 mg$397In Stock
50 mg$596In Stock
100 mg$858In Stock
200 mg$1,150In Stock
1 mL x 10 mM (in DMSO)$163In Stock
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Product Introduction

Bioactivity
Description
IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.
Targets&IC50
cGAS:2.1 nM (IC50), IRAK4:2.8 nM (IC50)
Chemical Properties
Molecular Weight340.37
FormulaC22H16N2O2
Cas No.1850276-58-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 24 mg/mL (70.51 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9380 mL14.6899 mL29.3798 mL146.8990 mL
5 mM0.5876 mL2.9380 mL5.8760 mL29.3798 mL
10 mM0.2938 mL1.4690 mL2.9380 mL14.6899 mL
20 mM0.1469 mL0.7345 mL1.4690 mL7.3449 mL
50 mM0.0588 mL0.2938 mL0.5876 mL2.9380 mL

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