Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Kaerophyllin has anti-fibrotic effects, it can protect the rat liver from TAA-caused injury and fibrogenesis by suppressing hepatic inflammation and inhibiting HSC activation, possibly through upregulation of PPAR-γ expression. Kaerophyllin inhibits AB-induced LX-2 activation and migration with downregulation of Akt/ERK phosphorylations and NF-κB activity.
Description | Kaerophyllin has anti-fibrotic effects, it can protect the rat liver from TAA-caused injury and fibrogenesis by suppressing hepatic inflammation and inhibiting HSC activation, possibly through upregulation of PPAR-γ expression. Kaerophyllin inhibits AB-induced LX-2 activation and migration with downregulation of Akt/ERK phosphorylations and NF-κB activity. |
Molecular Weight | 368.38 |
Formula | C21H20O6 |
CAS No. | 75590-33-9 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
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Kaerophyllin 75590-33-9 Apoptosis Cytoskeletal Signaling DNA Damage/DNA Repair Immunology/Inflammation MAPK Metabolism NF-Κb PI3K/Akt/mTOR signaling Akt PPAR NF-κB TNF ERK IL Receptor Inhibitor inhibitor inhibit