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L-701324

Catalog No. T1909   CAS 142326-59-8
Synonyms: L701324

L-701324 is an NMDA receptor with high affinity and selectivity for the glycine site, used as an orally active and long-acting anticonvulsant.

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L-701324 Chemical Structure
L-701324, CAS 142326-59-8
Pack Size Availability Price/USD Quantity
5 mg In stock $ 56.00
10 mg In stock $ 93.00
25 mg In stock $ 166.00
50 mg In stock $ 276.00
100 mg In stock $ 412.00
500 mg In stock $ 939.00
1 mL * 10 mM (in DMSO) In stock $ 62.00
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Purity: 100%
Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description L-701324 is an NMDA receptor with high affinity and selectivity for the glycine site, used as an orally active and long-acting anticonvulsant.
Kinase Assay Ovaries from mice at day10 of age are treated with 10 μM MHY1485 for 3h and proteins are extracted using M-PER Mammalian Protein Extraction Reagent containing a protease inhibitor cocktail. Protein concentrations in supernatants are determined by the bicinchoninic acid method. Equal amounts of protein lysates are loaded on 4-12% NuPAGE Bis-Tris gels in MOPS buffer and transferred to 0.45 μM pore nitrocellulose membranes[2].
Synonyms L701324
Molecular Weight 363.79
Formula C21H14ClNO3
CAS No. 142326-59-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 34 mg/mL

TargetMolReferences and Literature

1. Wlaź P, Poleszak E. Pharmacol Rep. 2011;63(5):1231-4.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Neurodegenerative Disease Compound Library ReFRAME Related Library Orally Active Compound Library Preclinical Compound Library Bioactive Compounds Library Max CNS-Penetrant Compound Library Anti-Alzheimer's Disease Compound Library Neurotransmitter Receptor Compound Library Anti-Parkinson's Disease Compound Library Bioactive Compound Library

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Keywords

L-701324 142326-59-8 Membrane transporter/Ion channel Neuroscience NMDAR iGluR Ionotropic glutamate receptors inhibit Inhibitor tail suspension test L 701324 chronic unpredictable mild stress antidepressant forced swim test glycine B binding site brain membranes L701324 inhibitor

 

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