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Ligustilide
3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.
Catalog No. T5S1287Cas No. 4431-01-0
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Purity:98.14%
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Ligustilide
Catalog No. T5S1287Cas No. 4431-01-0
3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $34 | In Stock | |
| 5 mg | $72 | In Stock | |
| 10 mg | $98 | In Stock | |
| 25 mg | $168 | In Stock | |
| 50 mg | $249 | In Stock | |
| 100 mg | $369 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | 3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis. |
| In vitro | To investigate the neuroprotective of ligustilide (LIG) against glutamate-induced apoptosis of PC12 cells, cell viability were examined by MTT assay. Pretreatment with ligustilide (1, 5, 15 μmol · L(-1)) significantly improved cell viability. The apoptosis rate in glutamate-induced PC12 cells was 13.39%, and decreased in the presence of ligustilide (1, 5, 15 μmol · L(-1)) by 9.06%, 6.48%, 3.82%, separately. Extracellular accumulation of Ca2+ induced by glutamate were significantly reduced by ligustilide . |
| Molecular Weight | 190.24 |
| Formula | C12H14O2 |
| Cas No. | 4431-01-0 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 1.9 mg/mL (10 mM), Sonication is recommended. (The compound is unstable in solution, please use soon.)  | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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