Nodakenin ((+)-Marmesinin) is a compound with anti-allergic and anti-inflammatory activities.

3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.

1. Byakangelicol may inhibit P-gp expressed at the BBB even under in vivo conditions. 2. Byakangelicol can inhibit IL-1beta-induced PGE2 release in A549 cells; this inhibition may be mediated by suppression of COX-2 expression and the activity of COX-2 en

1. Oxypeucedanin ((+-)-Oxypeucedanin) has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU145 cells. 2. Oxypeucedanin is a kind of open-channel blocker of the hKv1.5 channel and it prolongs the APD; therefore, it is an excellent candidate as an antiarrhythmic drug for atrial fibrillation.

1. (+)-(3R,8S)-Falcarindiol is a potential new anticancer agent that exerts its activity through inducing ER stress and apoptosis. 2. Falcarindiol induces immunosuppressive effects in vitro and in vivo and might be a novel therapy for autoimmune or allergic diseases. 3. Falcarindiol has protective effect against CCl(4) toxicity , in part, be explained by anti-lipid peroxidation activity associated with the induction of the GSTs including GSTA4.

P-Hydroxyphenethyl trans-ferulate exhibits affinity toward 5-HT(7) receptors in a competitive binding assay. P-Hydroxyphenethyl trans-ferulate can double quinone reductase specific activity in Hepa 1c1c7 cells at a level of 2.1 microg/mL (6.6 microM).

Meranzin hydrate exhibits antidepressive and prokinetic-like effects through the regulation of the common mediator, the alpha 2-adrenoceptor , and α±-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors; it produces a rapid effect mediated by AMPA

7-Demethylsuberosin (7-demethylsuberosin) is a coumarin compound isolated from Angelica gigas Nakai,and has anti-inflammatory activity,and exhibited inhibitory effects on PGE2 production with the IC50 values of 9.42 μM.

Decursinol is isolated from the roots of Angelica Gigas with an antinociceptive effect. It also has anti-tumor and anti-metastasis activity.

Alloimperatorin (Prangenidin) exhibits in vitro antitumor activity in HL-60 acute myeloid leukemia cancer cells via inducing apoptosis, cell cycle disruption and inhibition of cell migration. It photosensitizes efficiently the hemolysis of erythrocytes.

3'- O- Acetylhamaudol, isolated from the roots of Angelica japonica, exhibits anti-tumor activity through dual actions, anti-angiogenesis and intestinal intraepithelial lymphocyte activation.

8-Hydroxybergapten may have anti-wrinkle activity.

(+)-Columbianetin ((S)-Columbianetin) is a new phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage, it also has antifungal activity. (+)-Columbianetin has anti-inflammatory effects, it promotes histamine release, and inhibits the histamine release by substance P, suggests that it may be helpful in regulating mast cell-mediated allergic inflammatory responses. (+)-Columbianetin can be effectively used to protect keratinocytes from UVB induced damage.

1. Levistolide A (Diligustilide) inhibits liver fibrosis and angiogenesis.

(+)-Columbianetin acetate (COLUMBIANETIN ACETATE) may be helpful in regulating mast cell-mediated allergic inflammatory responses.The absorption of (+)-Columbianetin acetate is a passive diffusion process without pH-dependent.

Suberosin exhibits anti-inflammatory, and anticoagulant activities, it also shows biting deterrent activity against Aedes aegypti, it may be useful for use as mosquito larvicidal agent.

Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion and inflammatory activation of cancer

Tiglic acid is a monocarboxylic unsaturated organic acid found in croton oil and several other natural products. It functions as a plant metabolite.

1. Oxypeucedanin hydrate (Prangolarin Hydrate) has antioxidant activity. 2. Oxypeucedanin hydrate is an antimutagenic agent. 3. Oxypeucedanin hydrate exhibits carbohydrate metabolizing enzymes inhibitory effect.

Angelic anhydride ((Z)-2-Methylbut-2-enoic anhydride) is a reagent in the improved synthesis of angelate esters, which are the active chemical behind the strong pain-relieving and spasmolytic action of extracts from the plant butterbur.

Angelicain, also known as Norcimifugin, is a component found in Cimicifuga foetida that exhibits anti-inflammatory activity.

Angelic Acid ((Z)-2-Methylbut-2-enoic acid) is a monocarboxylic unsaturated organic acid. Angelic acid esters are the active components of herbal medicine used against a wide range of various health disturbances including pains, fever, gout, heartburn, etc.

α-Angelica lactone has cardiotonic activity, may exert their effects by providing an increased contraction-dependent calcium pool to be released upon systolic depolarization.

Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the proliferation of cultured human tumor

2'-Hydroxy-4'-methylacetophenone, a phenolic compound isolated from Angelicae koreana roots, possesses acaricidal properties and can be used in the preparation of 4'-methyl-2'-[(p-tolylsulfonyl)oxy]acetophenone.

(Rac)-Byakangelicin (7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-) is an antineoplastic agent.

2',4'-Dihydroxyacetophenone (Resacetophenone) is an alkyl-phenylketone.

Oxyimperatorin is a natural product from Angelica dahurica.

Dihydropashanone is a natural product of Angelica, Apiaceae. The catalog number is TN3858 and the CAS number is 41997-41-5. Dihydropashanone can be used as a reference standard.

Angelol G is a natural product from Angelica sinensis.

3'-Angeloyloxy-4'-senecioyloxy-2',3'-dihydrooroselol is a natural product for research related to life sciences. The catalog number is TN6597 and the CAS number is 1221686-60-7.

Angelicide is a natural product

6'-Feruloylnodakenin is a natural product for research related to life sciences. The catalog number is TN6473 and the CAS number is 131623-14-8.

Methyl Isoeugenol has antioxidant activity.

Angenomalin is a natural product

Tokinolide B may have sedative and spasmolytic properties.

Pangelin is a natural product

Angelol M shows activity in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells.

Columbianetin-beta-D-glucopyranoside exhibits anti-inflammatory and analgesic properties, it also shows strong inhibiting activity against platelet aggregation.

Angelol K shows significant activity on human platelet aggregation.

Angelol A and angelol B are passive diffusion as the dominating process in Caco-2 cell monolayer model.

(±)-Decursinol (3',4'-dihydro-3'-hydroxy-Xanthyletin) is a natural product from Angelica gigas.

(±)-Liquiritigenin ((±)-4',7-Dihydroxyflavanone), a flavonoid extracted from Angelica keiskei, inhibits the calcium-activated chloride channel TMEM16A.(±)-Liquiritigenin induces an increase in apoptosis and an enhancement of caspase3 activity. (±)-Liquiritigenin induces increased apoptosis and enhanced caspase3 activity. (±)-Liquiritigenin is used in breast cancer research.

Isosaxalin, heraclenin and heraclenol 3'-Me ether have melanin biosynthesis inhibitory activities.

5,6,7-Trimethoxycoumarin shows moderate inhibitory activity against Micrococcus luteus, it also displays an intermediate cytotoxic effects against brine shrimp larvae. 5,6,7-Trimethoxycoumarin can improve gastroprotective effects, and it has low toxicity

Angelicolide is a natural product of Angelica, Apiaceae. The catalog number is TMA2544 and the CAS number is 90826-58-7. Angelicolide can be used as a reference standard.

Khellactone shows antitumor activity,it can suppress the growth of NCI-H460 tumor cells. (+)-4'-cis-Khellactone and (+)-3'-cis-khellactone have antiplasmodial activities, they show notable inhibitory activity against -sensitive strains of with IC(50) values from 1.5 and 2.4 microM.

Neobyakangelicol has anti-lipolytic hormones effects, it can strongly inhibit insulin- stimulated lipogenesis.

Dehydrogeijerin significantly inhibits the inflammatory activity of activated macrophages, suggesting that it could be a potential candidate for the treatment of inflammatory disease.

Praeroside II shows inhibitory activity of NO production in macrophages.