DL-Mannitol is a osmotic diuretic, it may play a role in reducing off-target 68Ga-PSMA renal uptake

Praeruptorin B is an inhibitor of sterol regulatory element-binding proteins (SREBPs). It can also significantly up-regulate CYP3A4 expression and activity via the PXR-mediated pathway.

cis-Methylkhellactone is a natural product for research related to life sciences. The catalog number is TN3667 and the CAS number is 20107-13-5.

Qianhucoumarin E is a natural product of Peucedanum, Apiaceae. The catalog number is TN4873 and the CAS number is 156041-02-0. Qianhucoumarin E can be used as a reference standard.

Peucedanol 3'-O-glucoside is a natural product for research related to life sciences. The catalog number is TN4758 and the CAS number is 65891-61-4.

Peucedanocoumarin I is a natural product of Peucedanum, Apiaceae. The catalog number is TN4755 and the CAS number is 130464-55-0. Peucedanocoumarin I can be used as a reference standard.

trans-Methylkhellactone is a natural product for research related to life sciences. The catalog number is TN5167 and the CAS number is 23733-92-8.

Decursidate is a natural product of Peucedanum, Apiaceae. The catalog number is TN3788 and the CAS number is 272122-56-2. Decursidate can be used as a reference standard.

1. Praeruptorin C and E can relax swine coronary artery and decrease contractility in guinea-pig left atria, these effects are similar in many respects to those displayed by drugs that have calcium entry blocking activity. 2. Praeruptorin D and E can prot

(-)-Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities, it exerts distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis;it also can significantly suppress airway inflammation and airway remodeling induced by ovalbumin challenge, and is a potential candidate for the treatment of asthma. (-)-Praeruptorin A resensitizes Pgp-mediated MDR (Pgp-MDR) cancer cells to cancer drugs.

Decuroside I shows weak inhibiting activity against the primary and secondary wave aggregation of human platelet.

Peucedanocoumarin II shows only partial relaxation.

Decursitin D is a natural product from the roots of Peucedanum decursivum.

Peucedanol 7-O-glucoside is a natural product for research related to life sciences. The catalog number is TN4759 and the CAS number is 65853-04-5.

Peucedanocoumarin Ⅲ can induce rice resistance to blast disease.

1. Nodakenetin ((-)-Prangeferol) has clinical efficacy.

Apiosylskimmin is a natural product from Angelica gigas.

1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors and regulating the Bcl-2 family. 3.

1. Decursin (Decursinol angelate) is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug. 2. Decursin exhibits hepatoprotective effects , potentially by inhibiting the TGF-β1 induced NOX activation and Smad signaling. 3. Decursin has anti-cancer activity , mediated suppression of the PKCα, MAPK and NF-κB pathways in MCF-7 cells. 4. Decursin exhibits cytotoxicity against various human cancer cells and to possess anti-amnesic activity in vivo through the inhibition of AChE activity.

Praeruptorin A ((+)-Praeruptorin A) has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis.

trans-3'-O-Benzoyl-4'-O-methylkhellactone is a natural product for research related to life sciences. The catalog number is TN5163 and the CAS number is 23733-95-1.

Qianhucoumarin A is a natural product of Peucedanum, Apiaceae. The catalog number is TN4880 and the CAS number is 150135-35-6. Qianhucoumarin A can be used as a reference standard.

Oroselol, jatamansinol, nardostachysin, jatamansinone and nardosinone are Nardostachys jatamansi rhizome extract marker compounds.

trans-Khellactone is a natural product from Peucedanum wulongense.

1. Praeruptorin B can inhibit tumor promoter induced phemonenon in vitro.

(+)-Pteryxin ((+)-Pteryxin) has muscle-relaxant props. (+)-Pteryxin shows hepatoprotective and nitric oxide prodn. inhibitory activity.

(E)-Cinnamyl-(Z)-p-coumarate is a natural product for research related to life sciences. The catalog number is TN5923 and the CAS number is 391682-51-2.

Apterin has anti-inflammatory activity in vitro, it shows significantly inhibitory activity on nitric oxide production in RAW264.7 cells.

Qianhucoumarin G is a natural product from Peucedanum praeruptorum.

Selinidin decreases phosphorylation of phospholipase C-gamma1, p38 mitogen-activated protein kinase, and IkappaB-alpha upon FcepsilonRI stimulation.

Pd-C-II has anti-inflammation activity, it can inhibit TNF-α production and iNOS protein expression and inhibit COX-2 protein expression in LPS-stimulated RAW 264.7 cells. Pd-C-II inhibits anaphylactic mediator release from purified mast cells induced by

D-Mannitol (Mannitol) is a diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. D-Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.

(-)-Praeruptorin B is a natural product from Peucedanum praeruptorum Dunn.

1. (±)-Praeruptorin A could exhibit its anti-osteoclastogenic activity by inhibiting p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca(2+) oscillation 2. Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis. 3. Praeruptorin A and praeruptorin C can significantly upregulate multidrug resistance-associated protein 2 expression via the constitutive androstane receptor-mediated pathway in vitro, and this should be taken as an herb-drug interaction.