Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathway is likely involved.
Description | Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathway is likely involved. |
Targets&IC50 | PAI-1:26.10 μM |
Synonyms | 龙血素 B, 龙血素B |
Molecular Weight | 316.353 |
Formula | C18H20O5 |
CAS No. | 119425-90-0 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 150 mg/mL (474.16 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Loureirin B 119425-90-0 MAPK信号通路 代谢 离子通道 JNK ERK PAI-1 Potassium Channel Inhibitor inhibit KcsA Plasminogen activator inhibitor-1 Extracellular signal regulated kinases inhibitor