Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathway is likely involved.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 64.00 | |
5 mg | In stock | $ 147.00 | |
10 mg | In stock | $ 218.00 | |
25 mg | In stock | $ 369.00 | |
50 mg | In stock | $ 543.00 | |
100 mg | In stock | $ 776.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 159.00 |
Description | Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathway is likely involved. |
Targets&IC50 | PAI-1:26.10 μM |
Source |
Molecular Weight | 316.35 |
Formula | C18H20O5 |
CAS No. | 119425-90-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 150 mg/mL (474.16 mM)
You can also refer to dose conversion for different animals. More
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Loureirin B 119425-90-0 MAPK Membrane transporter/Ion channel Metabolism PAI-1 ERK Potassium Channel JNK Inhibitor inhibit KcsA Plasminogen activator inhibitor-1 Extracellular signal regulated kinases inhibitor