Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Luteolin (Luteolol) is a naturally occurring flavonoid. The flavonoids are polyphenolic compounds found as integral components of the human diet. In vitro work has concentrated on the direct and indirect actions of flavonoids on tumor cells, and has found a variety of anticancer effects such as cell growth and kinase activity inhibition, apoptosis induction, suppression of the secretion of matrix metalloproteinases and of tumor invasive behavior. Furthermore, some studies have reported the impairment of in vivo angiogenesis by dietary flavonoids. Experimental animal studies indicate that certain dietary flavonoids possess antitumoral activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 39.00 | |
50 mg | In stock | $ 45.00 | |
100 mg | In stock | $ 55.00 | |
200 mg | In stock | $ 86.00 | |
500 mg | In stock | $ 148.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 43.00 |
Description | Luteolin (Luteolol) is a naturally occurring flavonoid. The flavonoids are polyphenolic compounds found as integral components of the human diet. In vitro work has concentrated on the direct and indirect actions of flavonoids on tumor cells, and has found a variety of anticancer effects such as cell growth and kinase activity inhibition, apoptosis induction, suppression of the secretion of matrix metalloproteinases and of tumor invasive behavior. Furthermore, some studies have reported the impairment of in vivo angiogenesis by dietary flavonoids. Experimental animal studies indicate that certain dietary flavonoids possess antitumoral activity. |
Targets&IC50 | PDE2:6.4 μM(Ki), PDE3:13.9 μM(Ki), PDE5:9.5 μM(Ki), PDE1:15.0 μM(Ki), PDE4:11.1 μM(Ki) |
Synonyms | Luteolol, Flacitran, Digitoflavone, Luteoline |
Molecular Weight | 286.24 |
Formula | C15H10O6 |
CAS No. | 491-70-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 57 mg/mL (199.13 mM)
Ethanol: 3 mg/mL (10.48 mM), warmed
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Luteolin 491-70-3 Apoptosis Autophagy Immunology/Inflammation Metabolism Nrf2 Endogenous Metabolite PDE inhibit Keap1-Nrf2 Luteolol Flacitran Digitoflavone Inhibitor Luteoline inhibitor