luteolin

Luteolin (Luteolol) belongs to the flavonoid group of natural products and is a Nrf2 inhibitor, PDE inhibitor. Luteolin has a wide range of biological activities including antitumor, antioxidant, anti-inflammatory, antimicrobial, antiviral, antiallergic, and procoagulant.

Luteolin-3',7-di-O-glucoside has anti-ulcer and antioxidant activities.

Luteolin-7-O-β-D-glucopyranoside is a chemical compound found in the aerial parts of Codonopsis nervosa.

Luteolin 7,3'-di-O-glucuronide is a natural product for research related to life sciences. The catalog number is TN4464 and the CAS number is 53965-08-5.

Luteolin 5-O-α2-glucopyranoside has antioxidant activity, it can inhibit lipid peroxidation, and has DPPH radical-scavenging activity.

Luteolin-7-O-α-L-arabinopyranosyl-(1→6)-β-D-glucopyranoside, a flavonoid, exhibits antiradical activity [1].

Luteolin-7-rutinoside has both antifungal activities and anti-arthritic, can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection.

Luteolin 5,3'-dimethyl ether is a natural product for research related to life sciences. The catalog number is TN5508 and the CAS number is 62346-14-9.

Luteolin 7-sulfate, derived from the marine plant Phyllospadix iwatensis Makino, suppresses TYR gene expression by intervening in a signaling pathway involving the cAMP-responsive element binding protein (CREB) and microphthalmia-associated transcription factor (MITF). This inhibition ultimately leads to a decrease in melanin synthesis.

Luteolin 5-rutinoside is a useful organic compound for research related to life sciences. The catalog number is T125918 and the CAS number is 140380-87-6.

Luteolin 5-methyl ether is a natural product for research related to life sciences. The catalog number is TN5506 and the CAS number is 58115-29-0.

Luteolin-4'-O-glucoside (Luteolin-4-o-glucoside) is an inhibitor of IL-5 (IC50 = 3.7 μM) with anti-complementary, antioxidant and anticancer activity.

8-C-(2-Rhamnosyl-6-deoxyhexopyranosulyl)luteolin is a useful organic compound for research related to life sciences. The catalog number is T123914 and the CAS number is 933463-03-7.

Luteolin 7-diglucuronide is the major flavonoid isolated from Verbena officinalis and Aloysia triphylla.

Luteolin-3-O-beta-D-glucuronide is active in the inhibition of nitrite production in macrophages.

Luteolin 7-O-glucuronide (Luteolin-7-glucuronide) possesses antioxidant activities.

1. Orientin (Luteolin-8-glucoside) may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vascular barrier integrity by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases. 3. Orientin has neuroprotection effect by the intracellular mediation of caspase activity; may alleviate cognitive deficits and oxidative stress in AD mice; can exert antidepressant-like effects on CUMS mice, specifically by improving central oxidative stress, neurotransmission, and neuroplasticity.

Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.

Isoorientin (Homoorientin) has antioxidant activity.

Diosmetin (Luteolin 4-methyl ether) has been found to act as a weak TrkB receptor agonist.

1. Hydroxygenkwanin (Luteolin 7-methylether) possesses significant the antioxidative activity . 2. Hydroxygenkwanin has cytotoxicity, may be an effective natural product to treat glioma, and the combination of Apigenin and Hydroxygenkwanin may be a promising method for glioma chemotherapy.

Orientin 2''-O-rhamnoside is a natural product for research related to life sciences. The catalog number is TN5525 and the CAS number is 81398-30-3.

Luteolinidin chloride is a natural product. It is a potent CD38 inhibitor which can protect the heart against I/R injury with preservation of eNOS function and prevention of endothelial dysfunction in vivo.

6-Hydroxyluteolin 7-glucoside is derived from Tanacetum parthenium and T. vulgare showing anti-inflammatory effects.

7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) has anti-inflammatory, antibacterial and antifungal activities, it also shows moderate antitrypanosomal activity with MIC value of 19.0 ug ml

5,7-Dimethoxyluteolin is a natural product from Hovenia acerba. 5,7-Dimethoxyluteolin is a dopamine transporter (DAT) activator with an EC50 of 3.417 μM.

8-C-Galactosylluteolin is a useful organic compound for research related to life sciences. The catalog number is T124540 and the CAS number is 61950-88-7.

Chrysoeriol-7-O-glucoside can strongly inhibit the classical pathway of the complement system.Chrysoeriol-7-O-d-glucoside and luteolin-7-O-d-glucoside can inhibit palmitic acid uptake into small intestinal brush border membrane, apigenin-7-O-d-glucoside can inhibit alpha-amylase activity; they can enhance norepinephrine-induced lipolysis in fat cells.

Erinacine P (compound 1), a precursor metabolite of luteolin, is derived from the mycelia of the basidiomycete Hericium erinaceum YB4-6237. This compound can undergo mild chemical conversion to Erinacine B, followed by transformation into Erinacine A [1].