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MK-0873
🥰Excellent
Catalog No. T33422Cas No. 500355-52-2
Alias MK0873, MK 0873
MK-0873 is a novel and potent selective phosphodiesterase 4 (PDE4) inhibitor.
MK-0873
🥰Excellent
Purity: 99.29%
Catalog No. T33422Alias MK0873, MK 0873Cas No. 500355-52-2
MK-0873 is a novel and potent selective phosphodiesterase 4 (PDE4) inhibitor.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $146 | In Stock | |
| 5 mg | $350 | In Stock | |
| 10 mg | $530 | In Stock | |
| 25 mg | $859 | In Stock | |
| 50 mg | $1,180 | In Stock | |
| 100 mg | $1,590 | In Stock | |
| 500 mg | $3,190 | In Stock |
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Purity:99.29%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | MK-0873 is a novel and potent selective phosphodiesterase 4 (PDE4) inhibitor. |
| In vitro | Eight healthy, non-smoking male subjects participated in this randomized, open-label, 2-period, cross-over study. In one period subjects received an oral dose of 2.5mg MK-0873 for 6 days co-administered with a single oral dose of 250 mg theophylline on day 5. The other period consisted of a single dose of 250 mg of theophylline on day 1. In each period, blood samples were collected at predefined time points. In this study, in a limited number of subjects, co-administration of oral MK-0873 did not affect the pharmacokinetics, safety, and tolerability of oral theophylline in non-smoking healthy male subjects.[3] |
| Alias | MK0873, MK 0873 |
| Molecular Weight | 422.44 |
| Formula | C25H18N4O3 |
| Cas No. | 500355-52-2 |
| Smiles | C(NC1CC1)(=O)C2=CN(C=3C(C2=O)=CC=CN3)C4=CC(C#CC5=CN(=O)=CC=C5)=CC=C4 |
| Relative Density. | 1.34 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 6.56 mg/mL (15.53 mM), Sonication is recommended.  | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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