Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ML-792 is a specific small ubiquitin-like modifier (SUMO)-activating enzyme (SAE) inhibitor. Compared with NAE/NEDD8 and UAE/ubiquitin (IC50s of 32 μM and <100 μM, respectively), ML-792 is an effective and selective inhibitor of SAE/SUMO1 and SAE/SUMO2 in enzymatic assays (IC50s of 3 and 11 nM, respectively).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 84.00 | |
2 mg | In stock | $ 122.00 | |
5 mg | In stock | $ 197.00 | |
10 mg | In stock | $ 289.00 | |
25 mg | In stock | $ 455.00 | |
50 mg | In stock | $ 622.00 | |
100 mg | In stock | $ 888.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 249.00 |
Description | ML-792 is a specific small ubiquitin-like modifier (SUMO)-activating enzyme (SAE) inhibitor. Compared with NAE/NEDD8 and UAE/ubiquitin (IC50s of 32 μM and >100 μM, respectively), ML-792 is an effective and selective inhibitor of SAE/SUMO1 and SAE/SUMO2 in enzymatic assays (IC50s of 3 and 11 nM, respectively). |
Targets&IC50 | SAE/SUMO2:11 nM, SAE/SUMO1:3 nM |
Molecular Weight | 551.41 |
Formula | C21H23BrN6O5S |
CAS No. | 1644342-14-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (453.38 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
ML-792 1644342-14-2 Ubiquitination E1/E2/E3 Enzyme E2 conjugating enzyme Ubiquitin activating enzyme Ubiquitin conjugating enzyme inhibit ML 792 Ubiquitin ligase E3 ligating enzyme Inhibitor ML792 E1 activating enzyme inhibitor