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Montelukast

Catalog No. T1677 CAS 158966-92-8

Synonyms: Singular

Montelukast (Singular) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury.

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Montelukast, CAS 158966-92-8

Pack Size	Availability	Price/USD	Quantity
25 mg	In stock	$ 29.00
50 mg	In stock	Inquiry

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Purity: 100%

Purity: 99.74%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Singular
Molecular Weight	586.18
Formula	C35H36ClNO3S
CAS No.	158966-92-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 1.7 mM

DMSO: 170.6 mM, The compound is unstable in solution. Please use soon.

References and Literature

1. Zhang YJ, et al. Acta Pharmacol Sin. 2004 Oct;25(10):1341-6.

Citations

1. Chen X, Li C, Wang Z, et al.Computational screening of biomarkers and potential drugs for arthrofibrosis based on combination of sequencing and large nature language model.Journal of Orthopaedic Translation.2024, 44: 102-113.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Approved Drug Library Anti-Cancer Clinical Compound Library Anti-Cancer Drug Library Bioactive Compounds Library Max Anti-Cancer Compound Library Immunology/Inflammation Compound Library FDA-Approved Drug Library Oxidation-Reduction Compound Library Pediatric Drug Library Drug Repurposing Compound Library

Related Products

Related compounds with same targets

LTB4 antagonist 3 LTB4 antagonist 2 Etalocib Pobilukast ONO4057 5-O-Demethylnobiletin AZD9898 Tipelukast

Dose Conversion

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
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The answer of 19.713 mg appears in the Mass box

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Montelukast 158966-92-8 GPCR/G Protein Immunology/Inflammation Metabolism LTR Lipoxygenase Leukotriene Receptor intestinal COVID-19 asthma Cysltr1 liver icardiac ischemia–reperfusion inhibit MK-0476 damage cysteinyl leukotriene antioxidant Inhibitor MK0476 MK 0476 injury Singular inhibitor

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