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cysltr1

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CYSLTR1 Protein, Human, Recombinant (His)
Cysteinyl leukotriene receptor 1,G-protein coupled receptor HG55,Cysteinyl leukotriene D4 receptor,CysLTR1,CYSLTR1,CYSLT1,LTD4 receptor,HMTMF81
TMPH-03749
Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
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20 days
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