Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NUCC-390 dihydrochloride is selective agonist of small-molecule CXCR4 receptor.
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Description | NUCC-390 dihydrochloride is selective agonist of small-molecule CXCR4 receptor. |
In vitro | NUCC-390 dihydrochloride (10 μM;?pre-treatment 30 mins) leads to increased levels of pERK, it has the capability of stimulating signaling activity downstream of CXCR4 receptors[1].NUCC-390 (10 μM;?2 hours) can induce CXCR4 receptor internalization, and non-treated cells exhibit some diffuse expression of CXCR4-YFP throughout the cytosol and clear expression in the cell membrane in HEK cells[1]. |
In vivo | NUCC-390 dihydrochloride?contributes to the functional and anatomical recovery of the neuromuscular junction (NMJ) following an acute nerve terminal damage by α-LTx in CD-1 mice. |
Synonyms | NUCC-390 dihydrochloride |
Molecular Weight | 468.46 |
Formula | C23H35Cl2N5O |
CAS No. | T12269L |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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