Powder: -20°C for 3 years | In solvent: -80°C for 1 year
OR-1896 is an active long-lived Levosimendan metabolite, is a highly selective inhibitor of phosphodiesterase (PDE) III isoformand a powerful vasodilator.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 93.00 | |
5 mg | In stock | $ 228.00 | |
10 mg | In stock | $ 413.00 | |
25 mg | In stock | $ 892.00 | |
50 mg | In stock | $ 1,220.00 | |
100 mg | In stock | $ 1,650.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 253.00 |
Description | OR-1896 is an active long-lived Levosimendan metabolite, is a highly selective inhibitor of phosphodiesterase (PDE) III isoformand a powerful vasodilator. |
In vitro | OR-1896 evokes prominent vasodilatory responses, activation of ATP-sensitive sarcolemmal K+ channels of smooth muscle cells appears as a powerful vasodilator mechanism.?Additionally, activation of ATP-sensitive K+ channels in the mitochondria potentially extends the range of cellular actions towards the modulation of mitochondrial ATP production and implicates a pharmacological mechanism for cardioprotection[1]. |
Molecular Weight | 245.28 |
Formula | C13H15N3O2 |
CAS No. | 220246-81-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 62.5 mg/mL (254.81 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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OR-1896 220246-81-1 Metabolism PDE OR 1896 OR1896 inhibitor inhibit