store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a PROTAC coupler that targets SGK3 and binds ligand to VH032 VHL, which induces degradation of endogenous SGK3.PROTAC SGK3 degrader-1 inhibits GDC0941-induced proliferation of cancer cells.CAS 번호5017-88-83-4
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | Inquiry | $ 479.00 | |
5 mg | Inquiry | $ 977.00 | |
25 mg | Inquiry | $ 2,280.00 | |
50 mg | Inquiry | $ 2,970.00 | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 39.00 |
Description | PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a PROTAC coupler that targets SGK3 and binds ligand to VH032 VHL, which induces degradation of endogenous SGK3.PROTAC SGK3 degrader-1 inhibits GDC0941-induced proliferation of cancer cells.CAS 번호5017-88-83-4 |
In vitro | SGK3-PROTAC1 (0.3 μM) induces endogenous SGK3 degradation by 50% within 2 hours, with maximal degradation of 80% observed within 8 hours, accompanied by loss of phosphorylation of SGK3 substrate NDRG1[1]. |
Synonyms | SGK3-PROTAC1 |
Molecular Weight | 1157.38 |
Formula | C57H73FN10O11S2 |
CAS No. | 2381320-35-8 |
store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 80 mg/mL (69.12 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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PROTAC SGK3 degrader-1 2381320-35-8 Metabolism SGK PROTAC SGK3 degrader 1 PROTAC SGK-3 degrader-1 SGK3-PROTAC1 PROTAC SGK3 degrader1 inhibitor inhibit