Shopping Cart
- Remove All
Your shopping cart is currently empty
EMD638683 R-Form
😃Good
Catalog No. T11181Cas No. 1184940-47-3
EMD638683 is a highly selective SGK1 inhibitor with an IC50 of 3 μM. EMD638683 (R-Form) is the R-form of this compound.
EMD638683 R-Form
😃Good
Catalog No. T11181Cas No. 1184940-47-3
EMD638683 is a highly selective SGK1 inhibitor with an IC50 of 3 μM. EMD638683 (R-Form) is the R-form of this compound.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $193 | 5 days | |
| 5 mg | $327 | 5 days | |
| 25 mg | $766 | 8-10 weeks | |
| 50 mg | $996 | 8-10 weeks | |
| 100 mg | $1,750 | 8-10 weeks | |
| 1 mL x 10 mM (in DMSO) | $358 | 5 days |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "EMD638683 R-Form"
Ro-3306
Cited
T2356872573-93-8
RO-3306 is a selectivity ATP-competitive CDK1 inhibitor (Ki: 20 nM). The selectivity of RO-3306 for CDK1 is >15-fold higher than a diverse panel of human kinases.
- $32
Size
QTY
CitedGSK 650394
GSK650394
T2622890842-28-1
GSK 650394 is an inhibitor of serum- and glucocorticoid-regulated kinases (SGK) that inhibits SGK1 and SGK2 (IC50=62/103 nM). GSK 650394 has antitumor activity and also inhibits osteoclast differentiation and prevents bone loss.
- $34
Size
QTY
SGK1-IN-4
T99771628048-93-0
SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis.
- $113
Size
QTY
CKI-7
CKI-7 dihydrochloride, CKI7 dihydrochloride, CKI-7 2HCl, CKI7 2HCl, CKI 7 dihydrochloride, CKI 7 2HCl
T199131177141-67-1
CKI-7 is a potent, ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. It also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.
- $116
Size
QTY
SI-113 Cited
T95891392816-46-4
SI-113 is a potent and selective inhibitor of SGK1, a serine/threonine protein kinase, that modulates several oncogenic signaling cascades.
- $38
Size
QTY
CitedURMC-099
T60571229582-33-5
URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and also inhibits LRRK2 activity (IC50: 11 nM).
Aurora KinaseAutophagyBcr-AblCDKc-Met/HGFRDNA AlkylationIGF-1RLRRK2MEKMLKROCKSGKSrcSykTrk receptorVEGFR
- $52
Size
QTY
AT13148
T24821056901-62-2
AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.
- $41
Size
QTY
PROTAC SGK3 degrader-1
SGK3-PROTAC1
T138472381320-35-8
PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a PROTAC coupler that targets SGK3 and binds ligand to VH032 VHL, inducing degradation of endogenous SGK3. It inhibits GDC0941-induced proliferation of cancer cells. [5017-88-83-4]
- $479
Size
QTY
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | EMD638683 is a highly selective SGK1 inhibitor with an IC50 of 3 μM. EMD638683 (R-Form) is the R-form of this compound. |
| Molecular Weight | 364.34 |
| Formula | C18H18F2N2O4 |
| Cas No. | 1184940-47-3 |
| Relative Density. | 1.363 g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 180 mg/mL (494.04 mM), Sonication and heating are recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy EMD638683 R-Form | purchase EMD638683 R-Form | EMD638683 R-Form cost | order EMD638683 R-Form | EMD638683 R-Form chemical structure | EMD638683 R-Form formula | EMD638683 R-Form molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.