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RNAIII-inhibiting peptide TFA

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Purity:98.68%

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COA HNMR LCMS

RNAIII-inhibiting peptide TFA

Catalog No. TP1412

RNAIII-inhibiting peptide TFA (RNAIII-inhibiting peptide(TFA))(228544-21-6 free base) inhibits S. aureus, effective in the diseases such as cellulitis, keratitis, septic arthritis, osteomylitis and mastitis.

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Pack Size	Price	Availability
1 mg	$186	In Stock
5 mg	$598	In Stock
10 mg	$778	In Stock
25 mg	$1,010	In Stock
50 mg	$1,310	In Stock
100 mg	$1,710	In Stock
1 mL x 10 mM (in DMSO)	$788	In Stock

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Product Introduction

Bioactivity

Description	RNAIII-inhibiting peptide TFA (RNAIII-inhibiting peptide(TFA))(228544-21-6 free base) inhibits S. aureus, effective in the diseases such as cellulitis, keratitis, septic arthritis, osteomylitis and mastitis.
In vitro	The RNAIII inhibiting peptide (RIP) is able to inhibit S. aureus pathogenesis by disrupting QS mechanism competing with RAP, thus inhibiting the phosphorylation of TRAP. This alteration leads to a reduced adhesion and to the inhibition of RNAIII synthesis, with the subsequent suppression of toxins synthesis.
Alias	RNAIII-inhibiting peptide(TFA)

Chemical Properties

Molecular Weight	1027.01
Formula	C47H57F3N10O13
Cas No.

Storage & Solubility Information

Storage

keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 150 mg/mL (146.06 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	0.9737 mL	4.8685 mL	9.7370 mL	48.6850 mL
5 mM	0.1947 mL	0.9737 mL	1.9474 mL	9.7370 mL
10 mM	0.0974 mL	0.4869 mL	0.9737 mL	4.8685 mL
20 mM	0.0487 mL	0.2434 mL	0.4869 mL	2.4343 mL
50 mM	0.0195 mL	0.0974 mL	0.1947 mL	0.9737 mL
100 mM	0.0097 mL	0.0487 mL	0.0974 mL	0.4869 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

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