Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine. Sch 37370 blocks the binding of [3H]pyrilamine to histamine-H1 receptors in rat brain membranes. Sch 37370 selectively inhibits PAF-induced aggregation of human platelets (IC50 : 0.6 mM) and also competes with PAF binding to specific sites in membrane preparations from human lungs (IC50 : 1.2 mM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 95.00 | |
5 mg | In stock | $ 195.00 | |
10 mg | In stock | $ 279.00 | |
25 mg | In stock | $ 502.00 | |
50 mg | In stock | $ 728.00 | |
100 mg | In stock | $ 987.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 197.00 |
Description | SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine. Sch 37370 blocks the binding of [3H]pyrilamine to histamine-H1 receptors in rat brain membranes. Sch 37370 selectively inhibits PAF-induced aggregation of human platelets (IC50 : 0.6 mM) and also competes with PAF binding to specific sites in membrane preparations from human lungs (IC50 : 1.2 mM). |
Targets&IC50 | PAF:0.6 mM |
Molecular Weight | 352.86 |
Formula | C21H21ClN2O |
CAS No. | 117796-52-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/ml (85.02 mM)
You can also refer to dose conversion for different animals. More
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SCH-37370 117796-52-8 Others Platelet aggregation SCH37370 SCH 37370 inhibitor inhibit