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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $33 | In Stock | |
2 mg | $47 | In Stock | |
5 mg | $75 | In Stock | |
10 mg | $108 | In Stock | |
25 mg | $183 | In Stock | |
50 mg | $272 | In Stock | |
100 mg | $396 | In Stock | |
200 mg | $743 | In Stock | |
500 mg | $1,450 | In Stock |
Description | Thalidomide-O-amido-PEG2-C2-NH2 TFA (E3 Ligase Ligand-Linker Conjugates 24 TFA) is a synthesized E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a 2-unit PEG linker, utilized in PROTAC technology. |
In vitro | PROTACs consist of two ligands linked together: one binds to an E3 ubiquitin ligase, and the other targets a specific protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs facilitate the selective degradation of target proteins [1]. |
Alias | E3 Ligase Ligand-Linker Conjugates 24 TFA, Cereblon Ligand-Linker Conjugates 10 TFA |
Molecular Weight | 576.48 |
Formula | C23H27F3N4O10 |
Cas No. | 1957235-75-4 |
Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | H2O: 150 mg/mL (260.20 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O
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