Powder: -20°C for 3 years | In solvent: -80°C for 1 year
UCPH-101 is an inhibitor of excitatory amino acid transporter subtype 1 (EAAT1) with an IC50 of 0.66 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 45.00 | |
2 mg | In stock | $ 81.00 | |
5 mg | In stock | $ 148.00 | |
10 mg | In stock | $ 255.00 | |
25 mg | In stock | $ 536.00 | |
50 mg | In stock | $ 773.00 | |
100 mg | In stock | $ 1,080.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 163.00 |
Description | UCPH-101 is an inhibitor of excitatory amino acid transporter subtype 1 (EAAT1) with an IC50 of 0.66 μM. |
Targets&IC50 | EAAT1:0.66 μM. |
In vitro | Preincubation with 100 μM UCPH-101 results in a notable reduction in the expression levels of HA-EAAT1 and HA-GLAST. Additionally, UCPH-101 and UCPH-102 exhibit concentration-dependent inhibition of EAAT1 anion currents, with dissociation constant (KD) values of 0.34±0.03 μM (Hill=1.3±0.13, n≥9) for UCPH-101 and 0.17±0.02 μM (Hill=0.97±0.11, n≥7) for UCPH-102. |
Synonyms | UCPH 101 |
Molecular Weight | 422.48 |
Formula | C27H22N2O3 |
CAS No. | 1118460-77-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10.6 mg/mL(25 mM)
You can also refer to dose conversion for different animals. More
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UCPH-101 1118460-77-7 Metabolism transporter inhibit UCPH101 Inhibitor UCPH 101 inhibitor