Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Uncarinic acid E has anti-cancer activity, it induces apoptosis in HepG2 cells via accumulation of p53, alters the Bax/Bcl-2 ratio, and activates caspases, resulting in cytochrome c release from the mitochondria. A mixture of uncarinic acid E and 27-O-p-(E)-coumaroyloxyursolic acid exhibits antiplasmodial activity, with the IC50 value of 2.9 microg/ml.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 590.00 | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 910.00 |
Description | Uncarinic acid E has anti-cancer activity, it induces apoptosis in HepG2 cells via accumulation of p53, alters the Bax/Bcl-2 ratio, and activates caspases, resulting in cytochrome c release from the mitochondria. A mixture of uncarinic acid E and 27-O-p-(E)-coumaroyloxyursolic acid exhibits antiplasmodial activity, with the IC50 value of 2.9 microg/ml. |
Source |
Molecular Weight | 618.84 |
Formula | C39H54O6 |
CAS No. | 277751-61-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Uncarinic acid E 277751-61-8 Apoptosis MAPK Microbiology/Virology PI3K/Akt/mTOR signaling Proteases/Proteasome BCL Caspase p53 Antifection PI3K MEK inhibitor inhibit