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Acetylarenobufagin
🥰Excellent
Catalog No. T10233Cas No. 184673-79-8
Acetylarenobufagin is a steroidal hypoxia-inducible factor-1 (HIF-1) modulator.
Acetylarenobufagin
🥰Excellent
Purity: 98.54%
Catalog No. T10233Cas No. 184673-79-8
Acetylarenobufagin is a steroidal hypoxia-inducible factor-1 (HIF-1) modulator.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $105 | In Stock | |
| 2 mg | $178 | In Stock | |
| 5 mg | $297 | In Stock | |
| 10 mg | $415 | In Stock | |
| 25 mg | $654 | In Stock | |
| 50 mg | Inquiry | In Stock |
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View MoreInhibitors Related to "Acetylarenobufagin"
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1. Cinnamaldehyde (Cinnamic Aldehyde) has antipyretic activity. 2. Cinnamaldehyde is a sedative agent. 3. Cinnamaldehyde inhibits invasive capabilities of MDA-MB-435S cells was correlated with down-regulating the expression of miR-27a. 4. Cinnamaldehyde induces the generation of reactive oxygen species and exerts vasodilator and anticancer effects. 5. Cinnamaldehyde appears to be a promising candidate as an adjuvant in combination therapy with 5-fluorouracil (5-FU) and oxaliplatin (OXA), two chemotherapeutic agents used in CRC treatment. The possible mechanisms of its action may involve the regulation of drugmetabolizing genes. 6. Cinnamaldehyde plays a certain role in inhibiting the occurrence and progression of melanoma and its action mechanism may be manifested by inhibiting expression of VEGF and HIF-α, thus blood vessel simulation and formation of new blood vessels of melanoma cells, and growth of tumors accordingly.
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CitedZINC13466751
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ZINC13466751 is a potent HIF-1α/von Hippel-Lindau interaction inhibitor(IC50 of 2.0 µM).
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PX-478 Cited
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CitedVadadustat
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Vadadustat is a novel, titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor in development for the treatment of anemia.
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Roxadustat Cited
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Dapagliflozin Cited
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Acriflavine Hydrochloride
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DMOG Cited
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CitedPantoprazole sodium
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Pantoprazole sodium (Pantecta) is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole sodium is a lipophilic, weak base that crosses the parietal cell membrane and enters the acidic parietal cell canaliculus where it becomes protonated, producing the active metabolite sulfenamide, which forms an irreversible covalent bond with two sites of the H+/K+-ATPase enzyme located on the gastric parietal cell, thereby inhibiting both basal and stimulated gastric acid production.
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Purity:98.54%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Acetylarenobufagin is a steroidal hypoxia-inducible factor-1 (HIF-1) modulator. |
| Molecular Weight | 458.54 |
| Formula | C26H34O7 |
| Cas No. | 184673-79-8 |
| Smiles | C[C@@]12[C@@](O)([C@]3([C@]([C@H](O)C1=O)([C@]4(C)[C@](CC3)(C[C@@H](OC(C)=O)CC4)[H])[H])[H])CC[C@@H]2C=5C=CC(=O)OC5 |
| Relative Density. | 1.31 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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