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Amifloxacin
🥰Excellent
Catalog No. T17254Cas No. 86393-37-5
Alias Win49375
Amifloxacin (Win49375) is a synthetic antibacterial compound demonstrating moderate activity against Staphylococcus aureus, with MICs ≤ 2 micrograms/ml.
Amifloxacin
🥰Excellent
Purity: 98.1%
Catalog No. T17254Alias Win49375Cas No. 86393-37-5
Amifloxacin (Win49375) is a synthetic antibacterial compound demonstrating moderate activity against Staphylococcus aureus, with MICs ≤ 2 micrograms/ml.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $123 | In Stock | |
| 5 mg | $297 | In Stock | |
| 10 mg | $496 | In Stock | |
| 25 mg | $793 | In Stock | |
| 50 mg | $1,070 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $697 | In Stock |
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CitedSelect Batch
Purity:98.1%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Amifloxacin (Win49375) is a synthetic antibacterial compound demonstrating moderate activity against Staphylococcus aureus, with MICs ≤ 2 micrograms/ml. |
| Targets&IC50 | S. aureus:less than or equal to 2 μg/mL (MICs) |
| In vitro | The activity of Amifloxacin in vitro was comparable to those of norfloxacin and pefloxacin against Enterobacteriaceae and generally greater than those of tobramycin and cefotaxime. Amifloxacin was more active in vitro than carbenicillin and mezlocillin against Pseudomonas aeruginosa isolates[1]. |
| In vivo | Against systemic, gram-negative bacterial infections in mice, Amifloxacin was generally less active than cefotaxime but more active than gentamicin. WIN 49548, the major piperazinyl-N-desmethyl metabolite of Amifloxacin, was aa effective as the parent drug against experimental infections in mice when given parenterally. When administered orally, however, this metabolite was less potent than Amifloxacin. Amifloxacin was highly active by the oral route, with 50% effective doses within two- to threefold of those obtained with parenteral medication[1]. |
| Alias | Win49375 |
| Molecular Weight | 334.35 |
| Formula | C16H19FN4O3 |
| Cas No. | 86393-37-5 |
| Smiles | CNn1cc(C(O)=O)c(=O)c2cc(F)c(cc12)N1CCN(C)CC1 |
| Relative Density. | 1.44 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 4 mg/ml (11.96 mM)  | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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