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Anticancer agent 106
Anticancer agent 106
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Anticancer agent 106
Catalog No. T78958
Compound 106 (compound 10ic) induces apoptosis in B16-F10 melanoma cells and potently inhibits metastatic nodules in mouse models of lung metastatic melanoma, suggesting its utility in the study of cancer, particularly lung metastatic melanoma [1].
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Compound 106 (compound 10ic) induces apoptosis in B16-F10 melanoma cells and potently inhibits metastatic nodules in mouse models of lung metastatic melanoma, suggesting its utility in the study of cancer, particularly lung metastatic melanoma [1]. |
| In vitro | Anticancer agent 106 (Compound 106; 0.28-55 μM; 24 h) diminishes the viability of B16-F10 melanoma cells in a dose-dependent manner, with an IC50 of 4.8 μM [1]. At concentrations ranging from 5-20 μM over 48 hours, the same agent induces apoptosis in B16-F10 melanoma cells [1]. |
| In vivo | Anticancer agent 106 (9-9.5 mg/kg; i.p.; every 3rd day for 22 days) inhibits metastatic nodules in a murine model of pulmonary metastatic melanoma [1]. |
| Molecular Weight | 475.56 |
| Formula | C26H25N3O4S |
| Cas No. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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