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Anticancer agent 106
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Catalog No. T78958
Compound 106 (compound 10ic) induces apoptosis in B16-F10 melanoma cells and potently inhibits metastatic nodules in mouse models of lung metastatic melanoma, suggesting its utility in the study of cancer, particularly lung metastatic melanoma [1].
Anticancer agent 106
Anticancer agent 106
😃Good
Catalog No. T78958
Compound 106 (compound 10ic) induces apoptosis in B16-F10 melanoma cells and potently inhibits metastatic nodules in mouse models of lung metastatic melanoma, suggesting its utility in the study of cancer, particularly lung metastatic melanoma [1].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Compound 106 (compound 10ic) induces apoptosis in B16-F10 melanoma cells and potently inhibits metastatic nodules in mouse models of lung metastatic melanoma, suggesting its utility in the study of cancer, particularly lung metastatic melanoma [1]. |
| In vitro | Anticancer agent 106 (Compound 106; 0.28-55 μM; 24 h) diminishes the viability of B16-F10 melanoma cells in a dose-dependent manner, with an IC50 of 4.8 μM [1]. At concentrations ranging from 5-20 μM over 48 hours, the same agent induces apoptosis in B16-F10 melanoma cells [1]. |
| In vivo | Anticancer agent 106 (9-9.5 mg/kg, i.p., every 3rd day for 22 days) inhibits metastatic nodules in a murine model of pulmonary metastatic melanoma [1]. |
| Molecular Weight | 475.56 |
| Formula | C26H25N3O4S |
Storage & Solubility Information
| Storage | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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