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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $48 | In Stock | |
5 mg | $98 | In Stock | |
10 mg | $172 | In Stock | |
25 mg | $298 | In Stock | |
50 mg | $435 | In Stock | |
100 mg | $592 | In Stock | |
500 mg | $1,180 | In Stock | |
1 mL x 10 mM (in DMSO) | $139 | In Stock |
Description | Apyramide is an anti-inflammatory agent (NSAID) that acts as a prodrug of indomethacin, a potent, blood-brain permeable, and nonselective inhibitor of COX1 and COX2. |
In vivo | Apyramide demonstrates significantly lower toxicity in rats and mice compared to indomethacin when administered orally or via i.p. route. It shows anti-inflammatory effects on carrageenin-induced cotton pellet granuloma, paw edema, and adjuvant arthritis, as well as antipyretic and analgesic activities [1]. |
Molecular Weight | 490.93 |
Formula | C27H23ClN2O5 |
Cas No. | 68483-33-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 55 mg/mL (112.03 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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