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Bisabolangelone

🥰Excellent
Catalog No. TN1445Cas No. 30557-81-4

Bisabolangelone has anti-tumor, anti-inflammatory, anti-microbial, and antioxidant activities, it inhibits dendritic cell functions by blocking MAPK and NF-κB signaling.

Bisabolangelone

Bisabolangelone

🥰Excellent
Purity: 98.91%
Catalog No. TN1445Cas No. 30557-81-4
Bisabolangelone has anti-tumor, anti-inflammatory, anti-microbial, and antioxidant activities, it inhibits dendritic cell functions by blocking MAPK and NF-κB signaling.
Pack SizePriceAvailabilityQuantity
1 mg$44In Stock
5 mg$97In Stock
10 mg$164In Stock
25 mg$278In Stock
50 mgInquiryIn Stock
1 mL x 10 mM (in DMSO)$96In Stock
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Purity:98.91%
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Product Introduction

Bioactivity
Description
Bisabolangelone has anti-tumor, anti-inflammatory, anti-microbial, and antioxidant activities, it inhibits dendritic cell functions by blocking MAPK and NF-κB signaling.
In vitro
Bisabolangelone (BISA), isolated from the roots of Angelica koreana, has many pharmacological activities, such as anti-tumor, anti-microbial, antioxidant, and anti-inflammatory activities. BISA attenuated the production of pro-inflammatory cytokines including interleukin (IL)-12, IL-1β, and tumor necrosis factor-alpha (TNF-α), migration to macrophage inflammatory protein-3 beta, and allo-T cell activating ability of DCs. In addition, BISA affected endocytosis of DCs. Molecular studies showed that BISA suppressed MAPK phosphorylation and nuclear translocation of NF-κB p50/p65. BISA inhibited DC functions by blocking MAPK and NF-κB signaling[2].
Chemical Properties
Molecular Weight248.32
FormulaC15H20O3
Cas No.30557-81-4
Smiles[H][C@]12CC(C)=CC(=O)[C@@]1([H])[C@@](C)(O)\C(O2)=C\C=C(C)C
Relative Density.1.154 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 25 mg/mL (100.68 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.0271 mL20.1353 mL40.2706 mL201.3531 mL
5 mM0.8054 mL4.0271 mL8.0541 mL40.2706 mL
10 mM0.4027 mL2.0135 mL4.0271 mL20.1353 mL
20 mM0.2014 mL1.0068 mL2.0135 mL10.0677 mL
50 mM0.0805 mL0.4027 mL0.8054 mL4.0271 mL
100 mM0.0403 mL0.2014 mL0.4027 mL2.0135 mL

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