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PI3Kδ-IN-15
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Catalog No. T8651Cas No. 1146702-54-6
PI3Kδ-IN-15 is a selective PI3Kδ inhibitor that inhibits PI3Kδ more than 30-fold more effectively than PI3Kγ, PI3Kβ, and PI3Kα.
PI3Kδ-IN-15
PI3Kδ-IN-15
😃Good
Purity: 99.39%
Catalog No. T8651Cas No. 1146702-54-6
PI3Kδ-IN-15 is a selective PI3Kδ inhibitor that inhibits PI3Kδ more than 30-fold more effectively than PI3Kγ, PI3Kβ, and PI3Kα.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $30 | Backorder | |
| 10 mg | $43 | Backorder | |
| 25 mg | $70 | Backorder | |
| 50 mg | $89 | Backorder | |
| 100 mg | $128 | Backorder | |
| 200 mg | $193 | Backorder | |
| 1 mL x 10 mM (in DMSO) | $48 | Backorder |
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CitedSelect Batch
Purity:99.39%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | PI3Kδ-IN-15 is a selective PI3Kδ inhibitor that inhibits PI3Kδ more than 30-fold more effectively than PI3Kγ, PI3Kβ, and PI3Kα. |
| Targets&IC50 | p110δ (Cell-free assay):2.5 nM , p110γ (Cell-free assay):89 nM |
| In vitro | PI3Kδ-IN-15 exhibited excellent efficiencies with sub-nanomolar functional potency when compared with the reference PI3Kδ inhibitor. PI3Kδ IC50 = 0.5 nM, PI3KγIC50 = 15.3 nM, PI3KβIC50 = 145 nM, and PI3KαIC50 = 152 nM. [1] |
| Molecular Weight | 401.4 |
| Formula | C21H16FN7O |
| Cas No. | 1146702-54-6 |
| Smiles | [C@H](NC1=C2C(N=CN2)=NC=N1)(C)C=3N(C(=O)C=4C(N3)=CC=CC4F)C5=CC=CC=C5 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 25 mg/mL (60.18 mM)  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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