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Cefepime

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Cefepime

Catalog No. T0868LCas No. 88040-23-7

Cefepime (BMY-28142) is a cephalosporin antibiotic with antimicrobial activity, induces neurotoxicity, inhibits both Gram-positive and Gram-negative, and can be used in the study of anaerobic bacteria.

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Pack Size	Price	Availability
25 mg	$32	In Stock
50 mg	$40	In Stock
100 mg	$59	In Stock
1 mL x 10 mM (in DMSO)	$43	In Stock

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Product Introduction

Bioactivity

Description	Cefepime (BMY-28142) is a cephalosporin antibiotic with antimicrobial activity, induces neurotoxicity, inhibits both Gram-positive and Gram-negative, and can be used in the study of anaerobic bacteria.
In vivo	METHODS: Mice were given different doses of cisplatin (0, 10, 14, 18, 22, and 26 mg/kg) three days before intraperitoneal (ip) injection of 80 mg/kg cefepime to determine the dose of cisplatin that would not affect mouse survival and achieve human-like serum concentrations of cefepime. RESULTS: The half-life of cefepime was significantly prolonged at cisplatin doses of 18 and 22 mg/kg. [1]
Alias	BMY-28142

Chemical Properties

Molecular Weight	480.56
Formula	C19H24N6O5S2
Cas No.	88040-23-7

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 120 mg/mL (249.71 mM, Sonication is recommended.

H2O: 80 mg/mL (166.47 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0809 mL	10.4045 mL	20.8091 mL	104.0453 mL
5 mM	0.4162 mL	2.0809 mL	4.1618 mL	20.8091 mL
10 mM	0.2081 mL	1.0405 mL	2.0809 mL	10.4045 mL
20 mM	0.1040 mL	0.5202 mL	1.0405 mL	5.2023 mL
50 mM	0.0416 mL	0.2081 mL	0.4162 mL	2.0809 mL
100 mM	0.0208 mL	0.1040 mL	0.2081 mL	1.0405 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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