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Cefotiam hydrochloride

Cefotiam hydrochloride
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Purity:98.74%
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Cefotiam hydrochloride

Catalog No. T1616Cas No. 66309-69-1
Cefotiam hydrochloride (SCE-963 hydrochloride) is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.
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Pack SizePriceAvailabilityQuantity
10 mg$39In Stock
50 mg$55In Stock
100 mg$80In Stock
200 mg$118In Stock
500 mg$198In Stock
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Product Introduction

Bioactivity
Description
Cefotiam hydrochloride (SCE-963 hydrochloride) is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.
AliasPansporin, SCE-963 hydrochloride, Pansporine, Cefotiam dihydrochloride, Halospor
Chemical Properties
Molecular Weight598.6
FormulaC18H23N9O4S3.2HCl
Cas No.66309-69-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 50 mg/mL (83.53 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6706 mL8.3528 mL16.7056 mL83.5282 mL
5 mM0.3341 mL1.6706 mL3.3411 mL16.7056 mL
10 mM0.1671 mL0.8353 mL1.6706 mL8.3528 mL
20 mM0.0835 mL0.4176 mL0.8353 mL4.1764 mL
50 mM0.0334 mL0.1671 mL0.3341 mL1.6706 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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