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CFTR corrector 8 is a highly effective modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). This compound is specifically designed for utilization in research related to cystic fibrosis, a genetic disorder primarily affecting the lungs and digestive system [1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $44 | In Stock | |
5 mg | $107 | In Stock | |
10 mg | $167 | In Stock | |
25 mg | $337 | In Stock | |
50 mg | $530 | In Stock | |
100 mg | $870 | In Stock | |
200 mg | $1,170 | In Stock | |
1 mL x 10 mM (in DMSO) | $139 | In Stock |
Description | CFTR corrector 8 is a highly effective modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). This compound is specifically designed for utilization in research related to cystic fibrosis, a genetic disorder primarily affecting the lungs and digestive system [1]. |
In vitro | CFTR corrector 8 demonstrates EC50 values of 1 μM in the CSE-HRP assay and 3 μM in the HBE-TECC assay.[1] CFTR corrector 8 displays a hepatocyte clearance rate of 1250 L/hr/kg in humans and 775 L/hr/kg in rats.[1] |
Molecular Weight | 539.52 |
Formula | C29H27F2NO7 |
Cas No. | 1918142-35-4 |
Smiles | COc1ccc2[C@H](C[C@H](Oc2c1)c1ccc(OC)c(OC)c1)NC(=O)C1(CC1)c1ccc2OC(F)(F)Oc2c1 |
Storage | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | DMSO: 10 mg/mL (18.53 mM), Sonication is recommended. ![]() | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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