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Chebulagic acid
🥰Excellent
Catalog No. TQ0180Cas No. 23094-71-5
Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.
Chebulagic acid
🥰Excellent
Purity: 100%
Catalog No. TQ0180Cas No. 23094-71-5
Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 68 € | In Stock | |
| 5 mg | 159 € | In Stock | |
| 10 mg | 237 € | In Stock | |
| 25 mg | 397 € | In Stock | |
| 50 mg | 591 € | In Stock | |
| 100 mg | 842 € | In Stock | |
| 1 mL x 10 mM (in DMSO) | 256 € | In Stock |
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Purity:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor. |
| In vitro | Chebulagic acid can enhance autophagy and exerts anti-inflammatory and anti-infective effects [1,2]. Chebulagic acid also shows a protective effect against 1-methyl-4-phenylpyridinium (MPP+) - induce cytotoxicity which mimics the pathological symptom of Parkinson's disease. Chebulagic acid inhibits the LPS-induced upregulation of TNF-α and IL-1β in a dose- and time-dependent manner [3]. |
| Molecular Weight | 954.66 |
| Formula | C41H30O27 |
| Cas No. | 23094-71-5 |
| Smiles | O[C@H]1[C@H]2[C@H](CC(O)=O)C(=O)O[C@@H]3[C@H]4COC(=O)c5cc(O)c(O)c(O)c5-c5c(O)c(O)c(O)cc5C(=O)O[C@@H]3[C@@H](OC(=O)c3cc(O)c(O)c(OC1=O)c23)[C@H](OC(=O)c1cc(O)c(O)c(O)c1)O4 |
| Relative Density. | 2.13 g/cm3 |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 98 mg/mL (102.66 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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