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CKK-E12

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Catalog No. T74049Cas No. 1432494-65-9

CKK-E12 is a selective ionizable lipid that often binds to other lipids to form carrier mRNA lipid nanoparticles.CKK-E12 is used in the study of RNA-related diseases.

CKK-E12

CKK-E12

🥰Excellent
Purity: 98.328%
Catalog No. T74049Cas No. 1432494-65-9
CKK-E12 is a selective ionizable lipid that often binds to other lipids to form carrier mRNA lipid nanoparticles.CKK-E12 is used in the study of RNA-related diseases.
Pack SizePriceAvailabilityQuantity
1 mg$68In Stock
5 mg$163In Stock
10 mg$263In Stock
25 mg$529In Stock
1 mL x 10 mM (in DMSO)$288In Stock
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Purity:98.328%
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Product Introduction

Bioactivity
Description
CKK-E12 is a selective ionizable lipid that often binds to other lipids to form carrier mRNA lipid nanoparticles.CKK-E12 is used in the study of RNA-related diseases.
Chemical Properties
Molecular Weight993.62
FormulaC60H120N4O6
Cas No.1432494-65-9
SmilesO=C1NC(C(=O)NC1CCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)CCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC
Storage & Solubility Information
Storagestore at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 30 mg/mL (30.19 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.0064 mL5.0321 mL10.0642 mL50.3210 mL
5 mM0.2013 mL1.0064 mL2.0128 mL10.0642 mL
10 mM0.1006 mL0.5032 mL1.0064 mL5.0321 mL
20 mM0.0503 mL0.2516 mL0.5032 mL2.5161 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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